The Impact of Severe Hypoglycemia on Economic and Patient-Reported Outcomes

January 5, 2018. This observational, cross-sectional study found that reducing the frequency and severity of hypoglycemia could improve health-related quality of life (HRQoL) and reduce health care utilization and costs. Using data from the US National Health and Wellness Survey, the impact of hypoglycemia on health care resource utilization, HRQoL, work productivity and activity impairment, and estimated direct and indirect costs, were analyzed. Surveyed adults had type 2 diabetes and were using a basal insulin with oral antidiabetic drugs or rapid-acting/premixed insulins. Participants (N=2,423) were categorized according to hypoglycemia experience in the past 3 months: none (38.7%), non-severe (55.1%), and severe (6.2%). Patients with severe hypoglycemia had significantly (P<0.05) greater health care resource utilization, lower HRQoL scores, greater impairment in work productivity and activity, and higher costs vs those with no or non-severe hypoglycemia. The number of provider visits, HRQoL, and indirect costs were also affected in patients with non-severe hypoglycemia. You can access the study abstract here.